Article
Hepatocyte steatosis is a cytopathic effect of hepatitis C virus genotype 3.
Journal of hepatology - 1 Jul 2000
Rubbia-Brandt L, Quadri R, Abid K, Giostra E, Malé P J, Mentha G, Spahr L, Zarski J P, Borisch B, Hadengue A, Negro F
Abstract excerpt
BACKGROUND/AIMS: Patients infected with the hepatitis C virus (HCV) often have liver steatosis, suggesting the possibility of a viral cytopathic effect. The aim of this study was to correlate the occurrence and severity of liver steatosis with HCV RNA type, level and sequence of the core-encoding region. METHODS: We scored the liver steatosis in 101 HCV-infected individuals carefully selected to exclude other...
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