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Article

Viral sequence variation in chronic carriers of hepatitis C virus has a low impact on liver steatosis.

PloS one - 1 Jan 2012

Depla Marion, d'Alteroche Louis, Le Gouge Amélie, Moreau Alain, Hourioux Christophe, Meunier Jean-Christophe, Gaillard Julien, de Muret Anne, Bacq Yannick, Kazemi Farhad, Avargues Aurélie, Roch Emmanuelle, Piver Eric, Gaudy-Graffin Catherine, Giraudeau Bruno, Roingeard Philippe

Abstract excerpt

Most clinical studies suggest that the prevalence and severity of liver steatosis are higher in patients infected with hepatitis C virus (HCV) genotype 3 than in patients infected with other genotypes. This may reflect the diversity and specific intrinsic properties of genotype 3 virus proteins. We analyzed the possible association of particular residues of the HCV core and NS5A proteins known to dysregulate...

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Identifiers

PMID: 22479436
DOI: 10.1371/journal.pone.0033749
PMCID: PMC3315576

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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