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Article

Misexpression of Six2 is associated with heritable frontonasal dysplasia and renal hypoplasia in 3H1 Br mice.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jul 2008

Fogelgren Ben, Kuroyama Mari C, McBratney-Owen Brandeis, Spence Allyson A, Malahn Laura E, Anawati Mireille K, Cabatbat Chantelle, Alarcon Vernadeth B, Marikawa Yusuke, Lozanoff Scott

Abstract excerpt

A radiation-induced mouse mutant, Brachyrrhine (Br), exhibits frontonasal dysplasia and renal hypoplasia, two malformations associated with deficiencies in mesenchymal condensation. The purpose of this study was to resolve the Br locus, evaluate possible candidate genes, and identify developmenta...

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Identifiers

PMID: 18570229
DOI: 10.1002/dvdy.21587
PMCID: PMC2955765

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18570229-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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