Article
The influence of polymorphisms of glutathione S-transferases M1 and M3 on the development of human urothelial cancer.
Journal of toxicology and environmental health. Part A - 1 Jan 2008
Golka Klaus, Schmidt Tobias, Seidel Thilo, Dietrich Holger, Roemer Hermann C, Lohlein Dietrich, Reckwitz Thomas, Sokeland Jurgen, Weistenhofer Wobbeke, Blaszkewicz Meinolf, Selinski Silvia
Abstract excerpt
Cigarette smoking is the most important risk factor for development of transitional cell carcinoma of the urinary bladder. The effect of polymorphisms of glutathione S-transferases M1 (GSTM1) and M3 (GSTM3) on the influence of cigarette smoking on urinary bladder carcinogenesis was investigated. In total, 293 bladder cancer patients from hospitals in Dortmund and Wittenberg as well as 176 patients without any...
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