Article
TATA box-binding protein-associated factor 12 is important for RAS-induced transformation properties of colorectal cancer cells.
Molecular cancer research : MCR - 1 Jun 2008
Voulgari Angeliki, Voskou Stella, Tora Làszlò, Davidson Irwin, Sasazuki Takehiko, Shirasawa Senji, Pintzas Alexander
Abstract excerpt
Activating mutations in the RAS proto-oncogene result in constant stimulation of its downstream pathways, further leading to tumorigenesis. Transcription factor IID (TFIID) can be regulated by cellular signals to specifically alter transcription of particular subsets of genes. To investigate pote...
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