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Article

Cytokine gene polymorphism in kidney transplantation--impact of TGF-beta 1, TNF-alpha and IL-6 on graft outcome.

Transplant immunology - 1 Feb 2008

Nikolova Penka N, Ivanova Milena I, Mihailova Snejina M, Myhailova Anastassia P, Baltadjieva Daniela N, Simeonov Petar L, Paskalev Emil K, Naumova Elissaveta J

Abstract excerpt

Chronic allograft nephropathy (CAN) is one of the main causes of graft loss in renal transplantation. Polymorphisms with functional significance in the promoter and coding regions of cytokine genes have been suggested as a possible factor for graft rejection. The aim of this study was to investigate the impact of cytokine gene polymorphism of pro and anti-inflammatory cytokines on development of CAN in a group of...

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Source

Identifiers

PMID: 18158121
DOI: 10.1016/j.trim.2007.10.003

Genes

IFNG
TGFB1
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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