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Article

Systematic biological prioritization after a genome-wide association study: an application to nicotine dependence.

Bioinformatics (Oxford, England) - 15 Aug 2008

Saccone Scott F, Saccone Nancy L, Swan Gary E, Madden Pamela A F, Goate Alison M, Rice John P, Bierut Laura J

Abstract excerpt

MOTIVATION: A challenging problem after a genome-wide association study (GWAS) is to balance the statistical evidence of genotype-phenotype correlation with a priori evidence of biological relevance. RESULTS: We introduce a method for systematically prioritizing single nucleotide polymorphisms (S...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18565990
DOI: 10.1093/bioinformatics/btn315
PMCID: PMC2610477

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18565990-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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