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Multiplex ligation‐dependent probe amplification for detection of genomic alterations in chronic lymphocytic leukaemia

18 Jun 2008

Abstract excerpt

Chronic lymphocytic leukaemia (CLL) is the commonest form of leukaemia in adults in Western countries. We performed multiplex ligation-dependent probe amplification (MLPA) analysis in 50 CLL patients to identify multiple genomic CLL-specific targets, including genes located at 13q14, 17p13 (TP53), 11q23 (ATM) and chromosome 12, and compared the results with those obtained with fluorescence in situ hybridization...

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PMID: 18564355
DOI: 10.1111/j.1365-2141.2008.07268.x

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