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Article

Synergistic effects of angiotensinogen -217 G→A and T704C (M235T) variants on the risk of severe preeclampsia.

Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Jun 2014

Shahvaisizadeh Farhad, Movafagh Abolfazl, Omrani Mir Davood, Vaisi-Raygani Asad, Rahimi Ziba, Rahimi Zohreh

Abstract excerpt

BACKGROUND: The rate-limiting step of the renin-angiotensin system is the enzymatic cleavage of angiotensinogen (AGT) by renin. The aims of the present study were to investigate the association between AGT T704C (M235T) and -217 G→A polymorphisms with the risk of preeclampsia and synergistic effects of both polymorphisms on the susceptibility to preeclampsia. METHODS: We studied AGT variants in 170 women with...

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Source

Identifiers

PMID: 23178514
DOI: 10.1177/1470320312467555

Genes

AGT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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