Article
Laser microdissection allows detection of abnormal gene expression in cystic adenomatoid malformation of the lung.
Journal of pediatric surgery - 1 Jun 2008
Jancelewicz Tim, Nobuhara Kerilyn, Hawgood Sam
Abstract excerpt
BACKGROUND/PURPOSE: Congenital cystic adenomatoid malformation (CCAM) of the lung may result from a localized aberrant epithelial-mesenchymal interaction during lung development. We used laser microdissection (LMD) to isolate the epithelium and mesenchyme of CCAM, and studied candidate gene expression in these pure cell populations. METHODS: Congenital cystic adenomatoid malformation tissue was obtained from...
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