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Article

Genetic analysis of congenital cystic adenomatoid malformation reveals a novel pulmonary gene: fatty acid binding protein-7 (brain type).

Pediatric research - 1 Jul 2008

Wagner Amy J, Stumbaugh Amber, Tigue Zachary, Edmondson Jess, Paquet Agnes C, Farmer Diana L, Hawgood Samuel

Abstract excerpt

The pathogenesis of congenital cystic adenomatoid malformation (CCAM) is unknown and its natural history is unpredictable. Fatty acid binding protein-7 (FABP-7) has been previously described in brain and breast development, but never before in the lung. We investigate gene expression in CCAM, and hypothesize that CCAM results from an aberration in the signaling pathway during lung development. Under IRB approval,...

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PMID: 18391847
DOI: 10.1203/PDR.0b013e318174eff8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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