Article
On the origins of genetic variants.
FEBS letters - 22 Jul 1991
Wintersberger U
Abstract excerpt
Two contrasting mechanisms responsible for the creation of genetic variants are described: one is the manifestation of the limited accuracy of the cellular machinery for DNA replication, the other results from the ability of cells to repair damaged DNA. Replication-dependent variants and those caused by episodical DNA damage enhance the probability that a small fraction of a cell population may survive a sudden...
Topics
- Biological Evolution
- DNA Damage
- DNA Repair
- DNA Replication
- Escherichia coli
- Genetic Variation
- Mutation
- Selection, Genetic