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Article

Lethal mutants and truncated selection together solve a paradox of the origin of life.

PloS one - 1 Jan 2011

Saakian David B, Biebricher Christof K, Hu Chin-Kun

Abstract excerpt

BACKGROUND: Many attempts have been made to describe the origin of life, one of which is Eigen's cycle of autocatalytic reactions [Eigen M (1971) Naturwissenschaften 58, 465-523], in which primordial life molecules are replicated with limited accuracy through autocatalytic reactions. For successful evolution, the information carrier (either RNA or DNA or their precursor) must be transmitted to the next generation...

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Identifiers

PMID: 21814563
DOI: 10.1371/journal.pone.0021904
PMCID: PMC3144202

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Source receipt: pubmed, retrieved 7 Sept 2026.

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