Article
The Dutch hypothesis (chronic non-specific lung disease) revisited.
The European respiratory journal - 1 Apr 1991
Sluiter H J, Koëter G H, de Monchy J G, Postma D S, de Vries K, Orie N G
Abstract excerpt
In 1961 the hypothesis (later referred to as the Dutch Hypothesis (DH)) was put forward that asthma, chronic bronchitis and emphysema should be considered as different expressions of one disease entity, in which both endogenous (host) and exogenous (environmental) factors play a role in the pathogenesis. A hereditary predisposition to develop allergy and bronchial hyperreactivity were considered to be important...
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