Article
[Pathogenetic aspects of bronchial asthma].
Vestnik Rossiiskoi akademii meditsinskikh nauk - 1 Jan 2010
Kriuchkov N A
Abstract excerpt
This review represents contemporary knowledge about pathogenetic aspects of evolvement and progress of human bronchial asthma. Main attention is given to cells and mediators of allergic inflammation, Th1/Th2-bias, remodeling of respiratory tract, genetic and exogenous risk markers. Moreover, opportunities and prospects for the use of laboratory animals in modeling bronchial asthma are assessed.
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