Article
Genetic/environmental determinants of adult chronic obstructive pulmonary disease and possible links with childhood wheezing.
Paediatric respiratory reviews - 1 Jun 2001
Smith O O, Helms P J
Abstract excerpt
Epidemiological evidence and similarities in underlying inflammatory mechanisms suggest that childhood respiratory conditions and adult onset chronic obstructive pulmonary disease (COPD) may have a common aetiology. The prevalence of COPD in the UK has been estimated to be 10% in males and 11% in females, and like asthma, is thought to have a polygenic contribution with a complex interplay between genetic and...
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