Comprehensive analysis of the association of <scp><i>SCN1A</i></scp> gene polymorphisms with the retention rate of carbamazepine following monotherapy for new‐onset focal seizures in the <scp>C</scp>hinese <scp>H</scp>an population

Abstract excerpt

The aim of the present study was to investigate whether single nucleotide polymorphisms (SNPs) in the sodium channel a subunit type 1 (SCN1A) gene affect the retention rate of carbamazepine (CBZ) used to treat seizures in Chinese Han patients with epilepsy. In total, 448 patients were genotyped for SNPs selected in the SCN1A gene. The tag SNPs were selected using Haploview version 4.2 software...

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