Article
Differential association between human prostacyclin receptor polymorphisms and the development of venous thrombosis and intimal hyperplasia: a clinical biomarker study.
Pharmacogenetics and genomics - 1 Jul 2008
Patrignani Paola, Di Febbo Concetta, Tacconelli Stefania, Douville Karen, Guglielmi Maria D, Horvath Ryan J, Ding Min, Sierra Kent, Stitham Jeremiah, Gleim Scott, Baccante Giovanna, Moretta Valeria, Di Francesco Luigia, Capone Marta L, Porreca Ettore, Hwa John
Abstract excerpt
OBJECTIVE AND METHODS: The role of prostacyclin in the development of venous thrombosis and vascular dysfunction in humans is unclear. In patients with deep vein thrombosis (DVT, n=34) and controls (matched for age, sex, indexes of systemic inflammation and metabolic status, n=20), we studied (i) differences on systemic markers of vascular disease and platelet activation and (ii) the influence of prostacyclin...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.