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Article

Differential cancer predisposition in Lynch syndrome: insights from molecular analysis of brain and urinary tract tumors.

Carcinogenesis - 1 Jul 2008

Gylling A H S, Nieminen T T, Abdel-Rahman W M, Nuorva K, Juhola M, Joensuu E I, Järvinen H J, Mecklin J-P, Aarnio M, Peltomäki P T

Abstract excerpt

Hereditary non-polyposis colorectal carcinoma (Lynch syndrome) is among the most common hereditary cancers in man and a model of cancers arising through deficient DNA mismatch repair (MMR). Lynch syndrome patients are predisposed to different cancers in a non-random fashion, the basis of which is poorly understood. We addressed this issue by determining the molecular profiles for different tumors from a...

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PMID: 18550572
DOI: 10.1093/carcin/bgn133

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KRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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