Article
The use of chemokine antagonists in EAE models.
Journal of neuroimmunology - 31 Jul 2008
Proudfoot Amanda E I, de Souza Adriano Luís Soares, Muzio Valeria
Abstract excerpt
Multiple sclerosis is believed to be an autoimmune disease with an end-point of neuro-degeneration, but in which inflammation plays a predominant role. Therefore therapies which target inhibition of the excessive recruitment of leukocytes into the central nervous system (CNS) are actively sought after by medical research. Drug discovery relies heavily on animal models used for such research, called Experimental...
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