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Novel Zebrafish EAE model: A quick in vivo screen for multiple sclerosis.

Multiple sclerosis and related disorders - 1 Jan 2017

Kulkarni Pushkar, Yellanki Swapna, Medishetti Raghavender, Sriram Dharmarajan, Saxena Uday, Yogeeswari Perumal

Abstract excerpt

INTRODUCTION: Pre-clinical drug discovery for multiple sclerosis (MS) is a labor intensive activity to perform in rodent models. This is owing to the long duration of disease induction and observation of treatment effects in an experimental autoimmune encephalomyelitis (EAE) model. We propose a novel adult zebrafish based model which offers a quick and simple protocol that can used to screen candidates as a step...

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PMID: 28104252
DOI: 10.1016/j.msard.2016.11.010

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MOG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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