Article
TDP-43 in neurodegenerative disorders.
Expert opinion on biological therapy - 1 Jul 2008
Cook Casey, Zhang Yong-jie, Xu Ya-fei, Dickson Dennis W, Petrucelli Leonard
Abstract excerpt
BACKGROUND: The number of neurodegenerative diseases associated with pathological aggregates of transactivation response element (TAR)-DNA-binding protein 43 (TDP-43) has increased, leading to the new designation 'TDP-43 proteinopathy.' Biochemically, TDP-43 proteinopathies are characterized by d...
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