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Article

Exploring the energy landscape of antibody-antigen complexes: protein dynamics, flexibility, and molecular recognition.

Biochemistry - 8 Jul 2008

Thielges Megan C, Zimmermann Jörg, Yu Wayne, Oda Masayuki, Romesberg Floyd E

Abstract excerpt

The production of antibodies that selectively bind virtually any foreign compound is the hallmark of the immune system. While much is understood about how sequence diversity contributes to this remarkable feat of molecular recognition, little is known about how sequence diversity impacts antibody dynamics, which is also expected to contribute to molecular recognition. Toward this goal, we examined a panel of...

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Identifiers

PMID: 18549243
DOI: 10.1021/bi800374q

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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