Article
[Y chromosome and male infertility: what is a normal Y chromosome?].
Journal de la Societe de biologie - 1 Jan 2008
McElreavey Ken, Chantot-Bastaraud Sandra, Ravel Célia, Mandelbaum Jacqueline, Siffroi Jean-Pierre
Abstract excerpt
The human Y chromosome contains a number of genes and gene families that are essential for germ cell development and maintenance. Many of these genes are located in highly repetitive elements that are subject to rearrangements. Deletion of azoospermia factor (AZF) regions AZFa, AZFb, and AZFc are found in approximately 10-15% of men with severe forms of spermatogenic failure. Several partial AZFc deletions have...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
