Article
Y chromosome and male infertility.
Frontiers in bioscience : a journal and virtual library - 15 Jan 1999
Krausz C, McElreavey K
Abstract excerpt
Male factor infertility accounts for about half the cases of couple infertility. In more than 60% of cases the origin of reduced testicular function is unknown but they may have an unidentified genetic anomaly. Microdeletions of the long arm of the human Y chromosome are associated with spermatogenic failure and have been used to define three regions of Yq (AZFa, AZFb and AZFc) that are recurrently deleted in...
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