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Spectroscopical and mechanical characterization of normal and thalassemic red blood cells by Raman Tweezers

19 May 2008

Abstract excerpt

In this work, the effects of thalassemia, a blood disease quite diffuse in the Mediterranean sea region, have been investigated at single cell level using a Raman Tweezers system. By resonant excitation of hemoglobin Raman bands, we have examined the oxygenation capability of beta-thalassemic erythrocytes. A reduction of this fundamental erythrocyte function has been found. The measurements have been performed on...

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PMID: 18545504
DOI: 10.1364/oe.16.007943

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