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Article

Critical molecular regions for elicitation of the sweetness of the sweet-tasting protein, thaumatin I.

The FEBS journal - 1 Jul 2008

Ohta Keisuke, Masuda Tetsuya, Ide Nobuyuki, Kitabatake Naofumi

Abstract excerpt

Thaumatin is an intensely sweet-tasting protein. To identify the critical amino acid residue(s) responsible for elicitation of the sweetness of thaumatin, we prepared mutant thaumatin proteins, using Pichia pastoris, in which alanine residues were substituted for lysine or arginine residues, and the sweetness of each mutant protein was evaluated by sensory analysis in humans. Four lysine residues (K49, K67, K106...

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PMID: 18544096
DOI: 10.1111/j.1742-4658.2008.06509.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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