Article
[Relationship between the gene mutations of mannose binding protein and the progression of hepatitis B infection].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Jun 2008
Tong Fu-yi, Gan Jian-he, Lu Qin, Cao Wen-gui, Shen Xiu-juan
Abstract excerpt
OBJECTIVE: To investigate the relationship between the gene mutations of mannose binding protein(MBP) and the progression of hepatitis B. METHODS: The MBP gene mutations in 52 patients with chronic hepatitis B and 62 patients with severe hepatitis B and 64 HBsAg-negative healthy controls were investigated. The mutations in MBP gene were analyzed by polymerase chain reaction (PCR) and direct DNA sequencing....
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