Article
Evaluation of morphologic features to identify "basal-like phenotype" on core needle biopsies of breast.
Applied immunohistochemistry & molecular morphology : AIMM - 1 Oct 2008
Chivukula Mamatha, Striebel Joan M, Erşahin Cağatay, Dabbs David J
Abstract excerpt
The basal-like phenotype (BLP) subtype of breast carcinoma has been identified as 1 of 5 tumor subtypes first revealed by microarray profiling. This phenotype tends to be more aggressive, is more often associated with BRCA1 mutations, and carries a poor prognosis. Few studies have morphologically characterized BLP on resected breast specimens (RS), and no studies have evaluated these diagnostic parameters in core...
Topics
- Biopsy, Needle
- Breast
- Breast Neoplasms
- Carcinoma, Basal Cell
- Humans
- Phenotype
- Retrospective Studies