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Article

Centrally necrotizing carcinoma of the breast: clinicopathological analysis of 33 cases indicating its basal-like phenotype and poor prognosis.

Histopathology - 1 Aug 2010

Yu Lin, Yang Wentao, Cai Xu, Shi Daren, Fan Yuezhen, Lu Hongfen

Abstract excerpt

AIMS: To investigate the clinicopathological features and immunophenotype of centrally necrotizing carcinoma (CNC) of the breast to ascertain its relationship to basal-like phenotype and its prognosis. METHODS AND RESULTS: The clinical and pathological characteristics of 33 CNCs were reviewed. Immunohistochemical study of oestrogen receptor, progesterone receptor, HER2, cytokeratin (CK) 8/18,...

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PMID: 20716161
DOI: 10.1111/j.1365-2559.2010.03601.x

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