Centrally necrotizing carcinoma of the breast: clinicopathological analysis of 33 cases indicating its basal-like phenotype and poor prognosis.

doi:10.1111/j.1365-2559.2010.03601.x

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Article

Centrally necrotizing carcinoma of the breast: clinicopathological analysis of 33 cases indicating its basal-like phenotype and poor prognosis.

Histopathology - 1 Aug 2010

Yu Lin, Yang Wentao, Cai Xu, Shi Daren, Fan Yuezhen, Lu Hongfen

Abstract excerpt

AIMS: To investigate the clinicopathological features and immunophenotype of centrally necrotizing carcinoma (CNC) of the breast to ascertain its relationship to basal-like phenotype and its prognosis. METHODS AND RESULTS: The clinical and pathological characteristics of 33 CNCs were reviewed. Immunohistochemical study of oestrogen receptor, progesterone receptor, HER2, cytokeratin (CK) 8/18,...

Topics

Actins
Adult
Aged
Aged, 80 and over
Biomarkers, Tumor
Breast Neoplasms
ErbB Receptors
Female
Humans
Immunohistochemistry
Keratins
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Necrosis

Neoplasms, Hormone-Dependent

Phenotype

Prognosis

Receptor, ErbB-2

Receptors, Estrogen

Source

Open in PubMed

Identifiers

PMID: 20716161
DOI: 10.1111/j.1365-2559.2010.03601.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-20716161-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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