Article
Phenotypic and genotypic analyses of Neisseria gonorrhoeae isolates that express frequently recovered PorB PIA variable region types suggest that certain P1a porin sequences confer a selective advantage for urogenital tract infection.
Infection and immunity - 1 Aug 2008
Garvin Lotisha E, Bash Margaret C, Keys Christine, Warner Douglas M, Ram Sanjay, Shafer William M, Jerse Ann E
Abstract excerpt
Typing of the porB variable region (VR) is an epidemiological tool that classifies gonococcal strains based on sequence differences in regions of the porB gene that encode surface-exposed loops. The frequent isolation of certain porB VR types suggests that some porin sequences confer a selective advantage during infection and/or transmission. Alternatively, certain porin types may be markers of strains that are...
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