Article
Variation within serovars of Neisseria gonorrhoeae detected by structural analysis of outer-membrane protein PIB and by pulsed-field gel electrophoresis.
Microbiology (Reading, England) - 1 Apr 1997
Cooke Susan J, de la Paz Helen, La Poh Chit, Ison Catherine A, Heckels John E
Abstract excerpt
Outer-membrane protein PI is the antigen responsible for serovar specificity of Neisseria gonorrhoeae and is a potential vaccine target. In order to investigate possible hidden variation within a serovar, the sequence of the por genes encoding protein PIB have been obtained from a series of strai...
Topics
- Amino Acid Sequence
- DNA Restriction Enzymes
- DNA, Bacterial
- Electrophoresis, Gel, Pulsed-Field
- Epitope Mapping
- Female
- Genetic Variation
- Gonorrhea
- Humans
- Male
- Molecular Sequence Data
- Neisseria gonorrhoeae
- Porins
- Sequence Homology, Amino Acid
- Serotyping