Article
A typing system for neisseria gonorrhoeae based on biotinylated oligonucleotide probes to PIB gene variable regions.
The Journal of infectious diseases - 1 May 2000
Thompson D K, Deal C D, Ison C A, Zenilman J M, Bash M C
Abstract excerpt
The porin proteins PIA and PIB of Neisseria gonorrhoeae are serotyping antigens for the serovar classification system and leading candidates for gonococcal vaccine development. Although serotyping has been a useful tool, this method can be insensitive to critical sequence changes in the por gene, including those in surface-exposed variable regions (VRs). A sensitive and specific typing system for N. gonorrhoeae...
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