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Article

Polymorphisms within the adenosine receptor 2a gene are associated with adverse events in RA patients treated with MTX.

Rheumatology (Oxford, England) - 1 Aug 2008

Hider S L, Thomson W, Mack L F, Armstrong D J, Shadforth M, Bruce I N

Abstract excerpt

OBJECTIVE: To examine the role of adenosine receptor 2a gene (ADORA2a) polymorphisms on outcome of MTX treatment in RA. METHODS: Subjects included 309 RA patients with a defined response to MTX. Patients were included if they were (i) good responders (n = 147) (ESR <20 for >6/12 on stable dose of MTX) (ii) inefficacy failures (n = 101) (physician statement and failure to reduce ESR/CRP by 20%) or (iii) adverse...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18539621
DOI: 10.1093/rheumatology/ken182
PMCID: PMC2468887

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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