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Article

Evaluation of single-base substitution rate in DNA by affinity capillary electrophoresis.

Analytica chimica acta - 30 Jun 2008

Kanayama Naoki, Takarada Tohru, Shibata Hideaki, Kimura Ayumi, Maeda Mizuo

Abstract excerpt

Capillary electrophoretic separation of 60 mer single-stranded DNA (ssDNA) and a single-base-substituted ssDNA was demonstrated using a size- and composition-controlled poly(ethylene glycol)-oligodeoxyribonucleotide block copolymer (PEG-b-ODN) as an affinity ligand. Under appropriate conditions, PEG-b-ODN and ssDNA with a complementary sequence formed a reversible complex via hybridization during the...

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PMID: 18539181
DOI: 10.1016/j.aca.2008.02.021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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