Article
Plasmodium falciparum shows transcriptional versatility within the human host.
Trends in parasitology - 1 Jul 2008
Lovegrove Fiona E, Peña-Castillo Lourdes, Liles W Conrad, Hughes Timothy R, Kain Kevin C
Abstract excerpt
In a recent study published in Nature, Daily et al. profiled parasite gene expression in Plasmodium falciparum infections and identified three in vivo 'states' based on parasite transcription patterns. Despite similar host clinical features, two states displayed highly divergent gene expression, whereas the third was found in individuals with increased inflammatory markers. These findings suggest that parasites...
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