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Transcriptome profiling reveals functional variation in Plasmodium falciparum parasites from controlled human malaria infection studies

11 Sept 2019

Abstract excerpt

BACKGROUND: The transcriptome of Plasmodium falciparum clinical isolates varies according to strain, mosquito bites, disease severity and clinical history. Therefore, it remains a challenge to directly interpret the parasite's transcriptomic information into a more general biological signature in a natural human malaria infection. These confounding variations can be potentially overcome with parasites derived...

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PMID: 31521613
DOI: 10.1016/j.ebiom.2019.09.001

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