Article
Absence of the H2AX mutations in idiopathic infertile men with spermatogenic impairment.
Systems biology in reproductive medicine - 1 Jan 2000
Zhang Wei, Yang Yuan, Su Dan, Ma Yongxin, Zhang Sizhong
Abstract excerpt
H2AX is a histone H2A variant and one of the evolutionarily conserved fertility factors involved in DNA repair to maintain the genomic integrity and ensure the proper meiotic process. Male H2ax mutant mice are infertile and display defective meiosis. To investigate the possible association of var...
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