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Article

Emotional symptoms in children: The effect of maternal depression, life events, and COMT genotype.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Mar 2009

Evans Jonathan, Xu Ke, Heron Jon, Enoch Mary-Anne, Araya Ricardo, Lewis Glyn, Timpson Nic, Davies Simon, Nutt David, Goldman David

Abstract excerpt

Early adversity predicts anxiety and depression but variation in response to adversity is not understood. We investigated whether association between early adversity and emotional symptoms in young children differs according to variation of the COMT gene. The main outcome measure was the emotionality subscale of the Strengths and Difficulties Questionnaire (SDQ) completed by mothers for 8,431 children aged 6-7...

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Share to Catechol O-Methyltransferase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Depression, Postpartum

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Source

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Identifiers

PMID: 18535998
DOI: 10.1002/ajmg.b.30789
PMCID: PMC2746034

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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