Article
Stochastic modeling of human RBC alloimmunization: evidence for a distinct population of immunologic responders.
Blood - 15 Sept 2008
Higgins John M, Sloan Steven R
Abstract excerpt
Red blood cell (RBC) transfusion is unique as a common large-scale intravenous introduction of foreign tissue and provides a valuable opportunity to study human immunologic response to intravenous foreign antigen. Patients receiving RBC transfusions are at risk of forming alloantibodies against donor RBC antigens, and valid estimates of alloimmunization risk are clinically important, but little is known about the...
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