Article
Planarian neoblast micronucleus assay for evaluating genotoxicity.
Chemosphere - 1 Jul 2008
Knakievicz Tanise, Alves da Silveira Priscila, Ferreira Henrique Bunselmeyer
Abstract excerpt
Planarian neoblasts are somatic stem cells that have the potential to be used in genotoxicity assays due to their proliferative nature, sensitivity to genotoxic agents, and experimental accessibility. Two freshwater planarian species, Girardia tigrina and Girardia schubarti, were used to develop a neoblast-based micronucleus (MN) assay to assess genotoxicity. Intact or regenerating planarians were exposed to...
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