Article
Clonogenic neoblasts are pluripotent adult stem cells that underlie planarian regeneration.
Science (New York, N.Y.) - 13 May 2011
Wagner Daniel E, Wang Irving E, Reddien Peter W
Abstract excerpt
Pluripotent cells in the embryo can generate all cell types, but lineage-restricted cells are generally thought to replenish adult tissues. Planarians are flatworms and regenerate from tiny body fragments, a process requiring a population of proliferating cells (neoblasts). Whether regeneration is accomplished by pluripotent cells or by the collective activity of multiple lineage-restricted cell types is unknown....
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