Article
Podophyllum hexandrum ameliorates endosulfan-induced genotoxicity and mutagenicity in freshwater cyprinid fish crucian carp.
Pharmaceutical biology - 1 Dec 2017
Dar Sabzar Ahmad, Yousuf Abdul Rehman, Balkhi Masood-Ul-Hassan, Ganai Bashir Ahmad, Tantry Mudasir, Bhat Farooz Ahmad
Abstract excerpt
CONTEXT: Medicinal plants continue to act as a repository for novel drug leads with novel mechanisms of action. Podophyllum hexandrum Royale (Berberideceae) treats diverse conditions in folk medicine. OBJECTIVE: The antimutagenic potential of P. hexandrum was evaluated against endosulfan-induced clastogenicity in a piscine model by cytogenetic endpoints. MATERIALS AND METHODS: Podophyllum hexandrum rhizomes were...
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