Article
Diabetes insipidus.
Bailliere's clinical endocrinology and metabolism - 1 Jul 1995
Hendy G N, Bichet D G
Abstract excerpt
The advances in our understanding of the pathophysiology of defects in the antidiuretic hormone, the V2 receptor and the water channel, owing to mutations in the prepro-AVP-NPII, AVPR2 and AQP2 genes respectively, is providing insight into inherited diabetes insipidus as well as the more numerous sporadic cases. Further structure-function analyses of these mutated genes will increase our understanding of normal...
Topics
- Animals
- Diabetes Insipidus
- Diabetes Insipidus, Nephrogenic
- Genes, Dominant
- Genes, Recessive
- Humans
- Mutation
- Rats
- Receptors, Vasopressin