Article
Mutation patterns of mtDNA: empirical inferences for the coding region.
BMC evolutionary biology - 2 Jun 2008
Santos Cristina, Montiel Rafael, Arruda Adriana, Alvarez Luis, Aluja Maria Pilar, Lima Manuela
Abstract excerpt
BACKGROUND: Human mitochondrial DNA (mtDNA) has been extensively used in population and evolutionary genetics studies. Thus, a valid estimate of human mtDNA evolutionary rate is important in many research fields. The small number of estimations performed for the coding region of the molecule, showed important differences between phylogenetic and empirical approaches. We analyzed a portion of the coding region of...
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