Article
Association between mitochondrial DNA 10398A>G polymorphism and the volume of amygdala.
Genes, brain, and behavior - 1 Aug 2008
Yamasue H, Kakiuchi C, Tochigi M, Inoue H, Suga M, Abe O, Yamada H, Sasaki T, Rogers M A, Aoki S, Kato T, Kasai K
Abstract excerpt
Mitochondrial calcium regulation plays a number of important roles in neurons. Mitochondrial DNA (mtDNA) is highly polymorphic, and its interindividual variation is associated with various neuropsychiatric diseases and mental functions. An mtDNA polymorphism, 10398A>G, was reported to affect mitochondrial calcium regulation. Volume of hippocampus and amygdala is reportedly associated with various mental disorders...
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