Article
The cholesteryl ester transfer protein Taq1B gene polymorphism predicts clinical benefit of statin therapy in patients with significant coronary artery disease.
American heart journal - 1 Dec 2003
Carlquist John F, Muhlestein Joseph B, Horne Benjamin D, Hart Noal I, Bair Tami L, Molhuizen Henri O F, Anderson Jeffrey L
Abstract excerpt
BACKGROUND: Cholesteryl ester transfer protein (CETP) regulates plasma lipid distribution. A polymorphism in the CETP gene (Taq1B) is associated with CETP activity, HDL concentration, atherosclerosis progression, and response to statins, and may influence cardiovascular (CV) events. We studied CE...
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