Comparative characterization of a human large cell lung carcinoma cell line and the xenograft derived cell line.

doi:10.1016/0309-1651(91)90155-c

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Article

Comparative characterization of a human large cell lung carcinoma cell line and the xenograft derived cell line.

Cell biology international reports - 1 Mar 1991

Bonaldo M de F, Pestano C B, Ribeiro M C, Machado-Santelli G M, Mori L, Oliveira A R

Abstract excerpt

The HK-1 cell line established from a human large cell lung carcinoma shows a high transformed phenotype and undifferentiated characteristics. This cell line grows as an adherent monolayer in fetal calf serum-supplemented medium, shows a high proliferation index, is able to grow in semi-solid agar and is tumorigenic in athymic nude rats. The cell line HK-2 derived from the HK-1 xenograft in athymic nude rats...

Topics

Animals
Carcinoma, Non-Small-Cell Lung
Cell Division
Cell Line
DNA, Neoplasm
Glycosaminoglycans
Humans
Immunohistochemistry
Kinetics
Lung Neoplasms
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Neoplasm Transplantation

Phenotype

Rats

Rats, Nude

Transplantation, Heterologous

Tumor Cells, Cultured

Source

Open in PubMed

Identifiers

PMID: 1851672
DOI: 10.1016/0309-1651(91)90155-c

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1851672-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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