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Article

Comparative characterization of a human large cell lung carcinoma cell line and the xenograft derived cell line.

Cell biology international reports - 1 Mar 1991

Bonaldo M de F, Pestano C B, Ribeiro M C, Machado-Santelli G M, Mori L, Oliveira A R

Abstract excerpt

The HK-1 cell line established from a human large cell lung carcinoma shows a high transformed phenotype and undifferentiated characteristics. This cell line grows as an adherent monolayer in fetal calf serum-supplemented medium, shows a high proliferation index, is able to grow in semi-solid agar and is tumorigenic in athymic nude rats. The cell line HK-2 derived from the HK-1 xenograft in athymic nude rats...

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PMID: 1851672
DOI: 10.1016/0309-1651(91)90155-c

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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