Article
Identification and characterisation in vitro of cells with a non-SCLC cell-like phenotype derived from a continuous SCLC cell line.
Anticancer research - 1 Jan 2000
Khan M Z, Freshney R I, Murray A M, Merry S, Plumb J A, McNicol A M
Abstract excerpt
Two adherent sublines, H69V and H69VZ, have been isolated from the classic SCLC cell line NCI-H69. Significant morphological differences were observed between the parental and the derivative cell lines. While NCI-H69 grew as densely packed free floating cellular aggregates the derivative lines gr...
Topics
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Small Cell
- Creatine Kinase
- Dopa Decarboxylase
- Gastrin-Releasing Peptide
- Humans
- Isoenzymes
- Lung Neoplasms
- Male
- Peptides
- Phenotype
- Phosphopyruvate Hydratase
- Tumor Cells, Cultured