Article
Human endogenous retrovirus (HERV-K) reverse transcriptase as a breast cancer prognostic marker.
Neoplasia (New York, N.Y.) - 1 Jun 2008
Golan Maya, Hizi Amnon, Resau James H, Yaal-Hahoshen Neora, Reichman Hadar, Keydar Iafa, Tsarfaty Ilan
Abstract excerpt
A reverse transcriptase (RT) cDNA, designated HERV-K-T47D-RT, was isolated from a hormonally treated human breast cancer cell line. The protein product putative sequence is 97% identical to the human endogenous HERV-K retroviral sequences. Recombinant T47D-RT protein was used to generate polyclonal antibodies. The expression of HERV-K-T47D-RT protein increased in T47D cells after treatment with estrogen and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.